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Polycystic ovary syndrome (PCOS) is an endocrine disorder where the woman’s ovaries produce an excessive amount of male sex hormones called androgens, which are usually present in women in small amounts. In the condition, numerous small cysts (fluid-filled sacs) develop in the ovaries. Although, cysts occur in some women with this condition, but not by all of them.
Ovulation is the release of a mature egg from an ovary to be fertilised by a sperm. And if an egg is not fertilised, it is expelled from the body during menstruation. In rare instances, a woman does not produce enough ovulation-required hormones. In the absence of ovulation, the ovaries may generate several tiny cysts. These cysts produce androgen hormones. Frequently, the elevated androgen levels in women due to PCOS can exacerbate a woman’s menstrual cycle issues and induce a range of symptoms.
Typically, PCOS can be treated with medication. The meds do not cure PCOS, but it reduces symptoms and prevents health issues.
PCOS medicines that increase the likelihood of conception
Medicines that can help you ovulate and get pregnant are available on the advice of your doctor.
- Clomiphene (Clomid): An anti-estrogen medication, such as clomiphene, can be taken orally at the start of your menstrual cycle. Women with polycystic ovarian syndrome may benefit from combining clomiphene and metformin. After the first day of the menstrual cycle, the doctor may prescribe clomiphene as a 50ml pill for five days. A Clomid start date usually occurs on day 3, 4, or 5. Depending on how you will react to the drug, doctors may advise you to take one, two, three, or even four pills every day at the same time. Starting with the lowest dose and adjusting as necessary each month is customary. Some medical professionals may request that you return for hormone level blood tests or a transvaginal ultrasound to check your ovarian follicles.
- Benefits: There are advantages for persons receiving effective Clomid treatment, including: (1) It is one of the most affordable medicines for PCOS, (2) It is less invasive than other therapies because it is an oral drug,(3) You do not need to visit a reproductive expert to get it; your OB-GYN or doctor can prescribe it, and (4) There are few adverse effects and Clomid is typically well tolerated by women who take it.
- Gonadotropins: Gonadotrophins are the primary PCOS hormone medications for inducing ovulation in women with PCOS who did not ovulate or become pregnant while taking clomiphene citrate.
- Letrozole: Letrozole is an aromatase inhibitor (AI) used to induce ovulation in women. It inhibits the production of oestrogen by inhibiting aromatase. AIs are medications used to treat breast cancer in postmenopausal women and men. They are used to treat male gynecomastia as well. Letrozole inhibits oestrogen levels. Additionally, letrozole helps with ovulation in most women and pregnancy in more than 13% of cases. Studies have established that the medicine is effective and safe for treating infertility in women with PCOS.
- Metformin: Metformin is a medicine for PCOD & PCOS in women, and it can help those with prediabetes lose weight and avoid developing type 2 diabetes. Type 2 diabetes can be treated with oral medications by reducing insulin resistance and bringing insulin levels down to a more normal range. You can also be prescribed metformin to help induce ovulation if other meds fail to get you pregnant. However, you can consult your doctor about whether Metformin is suitable for you.