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An alpha-1 antitrypsin test is a type of test that assesses the amount of alpha-1 antitrypsin (AAT) in the bloodstream. AAT is a protein that is produced in the liver. This protein safeguards your lungs from damage and ailments, including emphysema and chronic obstructive pulmonary disease (COPD).
Certain genes in your body produce AAT. A person receives two copies of the gene that makes AAT, one from his father and another one from his mother. In case of any mutation in one or both copies of this gene, your body will produce less AAT or AAT that doesn’t function properly. If you carry two mutated copies of the gene, then you are suffering from a condition called AAT deficiency. But if you have one mutated AAT gene, you may produce a lower amount of AAT, but mild or no symptoms of the disease. These people are carriers of AAT deficiency. An AAT test determines whether you have the genetic mutation that makes you more prone to getting the risk for disease.
The cost of the alpha antitrypsin is Rs.1600 to Rs.1900, depending on your location and place.
Please check the price of the allergy test in Delhi/NCR, your nearby centers and other details.
Summary of Alpha 1 Antitrypsin Test
| Also known as | A1AT, AAT, Alpha-1-Antiprotease Deficiency, α1-Antitrypsin |
| Test Type | Blood |
| Alpha-1 antitrypsin includes | To check whether you have a lung infection or not |
| Preparation | You may not need any special preparations |
| Reporting | Within 24 hrs |
| Test price | The cost of the alpha antitrypsin is Rs.1600 to Rs.1900, depending on your location and place. |
| Also included in | Health Insurance Plans |
| Related tests | MRI, ECG, Echocardiogram, chest X-Ray, liver biopsy |
Purpose of AAT Test
An AAT test is recommended to diagnose AAT deficiency in people who are suffering from lung disease at an early age (45 years or younger) but don’t have other risk factors such as smoking. This test is also beneficial in diagnosing a rare form of liver disease in infants.
Your doctor will refer to this test if you are below 45 years and have symptoms of lung disease, including
- Wheezing
- Shortness of breath
- Chronic cough
- Abnormal heartbeat especially you stand up
- Vision problems
- Asthma that doesn’t get cured with a treatment
If you have a family history of AAT deficiency, then your doctor may suggest this test. Most people get this between their 20s and 40s.
In babies, AAT deficiency may affect the liver. So your baby may require an AAT test if his or her healthcare professional finds certain signs of liver disease. These include:
- Jaundice is a healthcare condition that makes your skin and eyes yellow for more than a week or two
- An enlarged spleen
- Difficulties in weight gain
- Frequent itching
- Nose or umbilical cord bleeding
Preparation of Alpha 1 Antitrypsin Test
This test doesn’t demand any kind of special preparation from the participants.
Procedure of AAT Test
- A deft nurse or technician will collect your blood sample by inserting a small needle from a vein in your arm.
- Once the needle is injected, a small amount of blood will be drawn into a test tube or vial.
- You may feel a sharp pain when the needle goes in or out.
- Your blood sample will be sent to the lab for further testing
- The entire process takes less than five minutes
Interpreting Results of Alpha 1 Antitrypsin Test
The normal level of AAT is between 100 and 300 mg/dL. Lesser than 80 mg/dL suggests that you have a significant risk of developing lung disease.
- If your results come up with a lower than normal amount of AAT, then you may have one or two mutated AAT genes.
- But if the level is too low, then you may have two mutated genes and AAT deficiency.
